Recombinant Human TNFRSF5/CD40 Protein

$660.00

Weight	3 lbs
Dimensions	5 × 5 × 5 in
Brand	ABclonal Technology
Size/Quantity	1-EA
Product Size	500 μg
Shipping Condition	Wet Ice
Manufacturer Part No	RP00543

SKU: Abclonal-RP00543 Category: Proteins

Description

Description

CD40 is a costimulatory protein found on antigen presenting cells and is required for their activation. The binding of CD154 (CD40L) on TH cells to CD40 activates antigen presenting cells and induces a variety of downstream effects.CD40 molecule is a potential target for cancer immunotherapy. There are number of completed and ongoing clinical trials where agonistic anti-CD40 monoclonal antibodies are employed to activate an anti-tumor T cell response via activation of dendritic cells.

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