Recombinant Mouse Amphiregulin/AREG Protein

$396.00

Weight 3 lbs
Dimensions 5 × 5 × 5 in
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SKU: Abclonal-RP03167 Category:

Description

Amphiregulin (AREG) is a ligand of the epidermal growth factor receptor (EGFR), a widely expressed transmembrane tyrosine kinase. AREG is synthesized as a membrane-anchored precursor protein that can engage in juxtacrine signaling on adjacent cells. Alternatively, after proteolytic processing by cell membrane proteases, mainly TACE/ADAM17, AREG is secreted and behaves as an autocrine or paracrine factor.

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