Recombinant Mouse CSF-1/M-CSF Protein

$123.20

Weight 3 lbs
Dimensions 5 × 5 × 5 in
Brand

Size/Quantity

Product Size

Shipping Condition

Manufacturer Part No

SKU: Abclonal-RP01216- 10 μg Category:

Description

Macrophage colony-stimulating factor 1, also known as CSF-1, M-CSF, is a single-pass membrane protein which is disulfide-linked as a homodimer or heterodimer. Granulocyte / macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. M-CSF/CSF-1 is known to facilitate monocyte survival, monocyte-to-macrophage conversion, and macrophage proliferation. M-CSF/CSF-1 is a secreted cytokine which influences hemopoietic stem cells to differentiate into macrophages or other related cell types. It binds to the Colony stimulating factor 1 receptor. M-CSF/CSF-1 may also be involved in development of the placenta. The active form of M-CSF/CSF-1 is found extracellularly as a disulfide-linked homodimer, and is thought to be produced by proteolytic cleavage of membrane-bound precursors. M-CSF/CSF-1 induces cells of the monocyte/macrophage lineage. It also plays a role in immunological defenses, bone metabolism, lipoproteins clearance, fertility and pregnancy. Upregulation of M-CSF/CSF-1 in the infarcted myocardium may have an active role in healing not only through its effects on cells of monocyte/macrophage lineage, but also by regulating endothelial cell chemokine expression.

Please Submit Your Inquiries Below
Name(Required)
This field is for validation purposes and should be left unchanged.

What Makes Us Unique?

Adva Tech Group, Inc. is a distributor of Life Science Reagents and Chemicals. Our customer base includes industries such as Advanced Technologies, Biologicals, Clinical, Controlled Environments and Cleanroom Solutions, Education, Environmental, Federal Government, Forensics, Food and Beverage, Industrial, Molecular Diagnostics, Petrochemical, Pharmaceuticals and Biotechnology, State and Local Government.

As a newly established supplier of chemicals and equipment, we offer a comprehensive supply of chemistry & laboratory equipment, designed to meet the rigorous demands of your research, experiments, and manufacturing needs. Our inventory offers everything from basic to advanced chemicals and equipment, ensuring that whether you are conducting complex chemical manufacturing or routine testing, you have access to top-quality chemistry & lab supplies.

Learn More