Recombinant Mouse Ep-CAM/TROP-1/CD326 Protein

$61.60

Weight 3 lbs
Dimensions 5 × 5 × 5 in
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SKU: Abclonal-RP01570- 10 μg Category:

Description

Epithelial Cellular Adhesion Molecule (Ep-CAM), also known as EGP314, mEGP314, Protein 289A, Tumor-associated calcium signal transducer 1, CD326, belongs to the EPCAM family. Its ’ monomer subunit structureinteracts with phosphorylated CLDN7. Ep-CAM may act as a physical homophilic interaction molecule betweenintestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium for providingimmunological barrier as a first line of defense against mucosal infection. It plays a role in embryonic stem cellsproliferation and differentiation. It also up-regulates the expression of FABP5, MYC and cyclins A and E. Thepost-translational modification glycosylation at Asn-198 is crucial for protein stability.

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