Recombinant Mouse Hepcidin/HAMP Protein

$440.00

Weight 3 lbs
Dimensions 5 × 5 × 5 in
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SKU: Abclonal-RP02870LQ- 100 μg Category:

Description

Hepcidin, the main regulator of iron metabolism, is synthesized and released by hepatocytes in response to increased body iron concentration and inflammation. Deregulation of hepcidin expression is a common feature of genetic and acquired iron disorders: in Hereditary Hemochromatosis (HH) and iron-loading anemias low hepcidin causes iron overload, while in Iron Refractory Iron Deficiency Anemia (IRIDA) and anemia of inflammation (AI), high hepcidin levels induce iron-restricted erythropoiesis.

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