Recombinant Mouse IgG2B Protein

$211.20

Weight 3 lbs
Dimensions 5 × 5 × 5 in
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SKU: Abclonal-RPT0025- 100 μg Category:

Description

IgG2b,Type I receptor for TGF-beta family ligands BMP9/GDF2 and BMP10 and important regulator of normal blood vessel development. On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. May bind activin as well.

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