Recombinant Mouse IL-1Ra/IL-1F3/IL-1RN Protein

$528.00

Weight 3 lbs
Dimensions 5 × 5 × 5 in
Brand

Size/Quantity

Product Size

Shipping Condition

Manufacturer Part No

SKU: Abclonal-RP00666- 100 μg Category:

Description

Interleukin-1 receptor antagonist protein (Il1rn), also known as IL-1ra, IRAP or IL1 inhibitor, is a member of theinterleukin 1 cytokine family. This protein inhibits the activities of interleukin 1 alpha (IL1A) and interleukin 1beta (IL1B), and modulates a variety of interleukin 1 related immune and inflammatory responses. The mouseIl1rn gene encodes a 178 amino acids (aa) protein with a 26 aa signal peptide. Mouse Il1rn protein shares 26%and 19% identity with its homologues IL-1 beta and IL-1 alpha, respectively. Il1rn can Inhibits the activity ofinterleukin-1 by binding to receptor IL1R1 and preventing its association with the coreceptor IL1RAP forsignaling, but has no interleukin-1 like activity. Recently, an recombinant human Il1rn protein is used in thetreatment of rheumatoid arthritis, an autoimmune disease in which IL-1 plays a key role.

Please Submit Your Inquiries Below
Name(Required)
This field is for validation purposes and should be left unchanged.

What Makes Us Unique?

Adva Tech Group, Inc. is a distributor of Life Science Reagents and Chemicals. Our customer base includes industries such as Advanced Technologies, Biologicals, Clinical, Controlled Environments and Cleanroom Solutions, Education, Environmental, Federal Government, Forensics, Food and Beverage, Industrial, Molecular Diagnostics, Petrochemical, Pharmaceuticals and Biotechnology, State and Local Government.

As a newly established supplier of chemicals and equipment, we offer a comprehensive supply of chemistry & laboratory equipment, designed to meet the rigorous demands of your research, experiments, and manufacturing needs. Our inventory offers everything from basic to advanced chemicals and equipment, ensuring that whether you are conducting complex chemical manufacturing or routine testing, you have access to top-quality chemistry & lab supplies.

Learn More