Recombinant Mouse PDGFR-alpha/CD140a Protein

$1,848.00

Weight 3 lbs
Dimensions 5 × 5 × 5 in
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SKU: Abclonal-RP00718- 500 μg Category:

Description

Platelet-derived growth factor receptors (PDGFR) are cell surface tyrosine kinase receptors for members of theplatelet-derived growth factor (PDGF) family. The PDGF family consists of PDGF-A, -B, -C and -D, which formeither homo- or heterodimers (PDGF-AA, -AB, -BB, -CC, -DD). The four PDGFs are inactive in their monomericforms. PDGFs bind to the protein tyrosine kinase receptors PDGF receptor- α and – β . These two receptorisoforms dimerize upon binding the PDGF dimer, leading to three possible receptor combinations, namely -αα,#NAMEsignaling has been linked to a number of proliferative disorders.

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