Recombinant Mouse SIRP-alpha/CD172a Protein

$294.40

Recombinant Mouse SIRP-alpha/CD172a Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Lys32-Asn373) of mouse SIRP-alpha/CD172a (Accession #NP_001277948.1) fused with a hFc tag at the C-terminus.

Weight 1.00 lbs
Dimensions 5.00 × 5.00 × 5.00 in
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SKU: Abclonal-RP01619-100UG
SKU: Abclonal-RP01619-100UG Category: Brand:

Description

Size quantity : 1-EA
Description : Signal regulatory protein α (SIRPα) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons.SIRPα acts as inhibitory receptor and interacts with a broadly expressed transmembrane protein CD47 also called the “don′t eat me” signal.Cancer cells highly expressed CD47 that activate SIRP α and inhibit macrophage-mediated destruction.

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