Recombinant Mouse SIRP-alpha/CD172a Protein

$79.20

Weight 3 lbs
Dimensions 5 × 5 × 5 in
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SKU: Abclonal-RP01619- 10 μg Category:

Description

Signal regulatory protein α (SIRPα) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons.SIRPα acts as inhibitory receptor and interacts with a broadly expressed transmembrane protein CD47 also called the “don′t eat me” signal.Cancer cells highly expressed CD47 that activate SIRP α and inhibit macrophage-mediated destruction.

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