Recombinant Mouse TNFRSF4/OX40/CD134 Protein

$88.00

Weight 3 lbs
Dimensions 5 × 5 × 5 in
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SKU: Abclonal-RP01324- 10 μg Category:

Description

OX40 (CD134) and its binding partner, OX40L (CD252), are members of the tumor necrosis factor receptor/tumor necrosis factor superfamily, is known to break an existing state of tolerance in malignancies, leading to a reactivation of antitumor immunity. The interaction between OX40 and OX40L plays an important role in antigen-specific T-cell expansion and survival. OX40 and OX40L also regulate cytokine production from T cells, antigen-presenting cells, natural killer cells, and natural killer T cells, and modulate cytokine receptor signaling.

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