Recombinant Mouse TNFSF5/CD40 ligand/CD154 Protein

$70.40

Weight 3 lbs
Dimensions 5 × 5 × 5 in
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SKU: Abclonal-RP01734- 10 μg Category:

Description

CD154, also known as CD40 ligand or CD40L, is a member of the TNF superfamily. While CD154 was originally found on T cell surface, its expression has since been found on a wide variety of cells, including platelets, mast cells, macrophages and NK cells. CD154’s ability is achieved through binding to the CD40 on antigen-presenting cells (APC). In the macrophage cells, the primary signal for activation is IFN-γ from Th1 type CD4 T cells. The secondary signal is CD40L on the T cell, which interacting with the CD40 molecules, helping increase the level of activation.

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