SRGAP2 Rabbit pAb

$229.46

Weight 3 lbs
Dimensions 5 × 5 × 5 in
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SKU: Abclonal-A19512 Category:

Description

This locus encodes a member of the SLIT-ROBO Rho GTPase activating protein family. The encoded protein stimulates GTPase activity of Rac1, and plays a role in cortical neuron development. This locus has several paralogs on human chromosome 1 resulting from segmental duplication. While this locus itself is conserved among various species, the paralogs are found only in the genus Homo, and not in the genomes of non-human great apes. Alternatively spliced transcript variants have been described for this locus.

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