Description
Streptomycin Sulfate is an aminoglucoside antibiotic in which streptidine is linked glycosidically to the disaccharide streptobiosamine. It is most active in a slightly alkaline medium. Inhibits initiation and causes misreading of rRNA in protein synthesis. Effective against gram-negative and gram-positive bacteria. About one-third of streptomycin in the circulation is bound to plasma proteins. About 30-90% of a dose is excreted unchanged in the urine in 24 hours.