Description
25-OH-VD, is the primary circulating form of vitamin D in human body after its initial metabolism. It serves as the preferred biomarker for assessing vitamin D status due to its plasma concentration accurately reflecting total body stores. Derived from the hydroxylation of vitamin D precursors (vitamin D3 or D2) in the liver, 25-OH-VD is a precursor to the biologically active 1,25-(OH)2-D3 formed in the kidneys. Its long half-life and stable levels make it the standard analyte for laboratory tests to diagnose vitamin D deficiency or excess, crucial in preventing and treating conditions like osteoporosis, rickets, and various chronic diseases linked to vitamin D, including cardiovascular issues, immune disorders, muscle dysfunction, diabetes, and certain cancers.