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Human GRO-α, GRO-β (MIP-2α), and GRO-γ (MIP-2β) are products of three distinct, nonallelichuman genes. GRO-β and GRO-γ share 90% and 86% amino acid sequence homology, respectively, with GROα. All three isoforms of GRO are CXC chemokines that can signal through the CXCR1 or CXCR2 receptors.GRO expression is inducible by serum or PDGF and/or by a variety of inflammatory mediators, such as IL-1 and TNF, in monocytes, fibroblasts, melanocytes and epithelial cells. In certain tumor cell lines, GRO is expressed constitutively.Similar to other alpha chemokines, the three GRO proteins are potent neutrophil attractants and activators. In addition, these chemokines are also active toward basophils.

Human GRO-α, GRO-β (MIP-2α), and GRO-γ (MIP-2β) are products of three distinct, nonallelichuman genes. GRO-β and GRO-γ share 90% and 86% amino acid sequence homology, respectively, with GROα. All three isoforms of GRO are CXC chemokines that can signal through the CXCR1 or CXCR2 receptors.GRO expression is inducible by serum or PDGF and/or by a variety of inflammatory mediators, such as IL-1 and TNF, in monocytes, fibroblasts, melanocytes and epithelial cells. In certain tumor cell lines, GRO is expressed constitutively.Similar to other alpha chemokines, the three GRO proteins are potent neutrophil attractants and activators. In addition, these chemokines are also active toward basophils.

GRO-α/KC/CXCL1 coded by CXCL1 gene at chromosome 5 is approximately 63% identity to that of mouse MIP2. KC is also approximately 60% identical to the human GROs. Mouse KC is a potent neutrophil attractant and activator. The functional receptor for KC has been identified as CXCR2. Based on the pattern of KC expression in a number of inflammatory disease models, KC appears to have an important role in inflammation. KC was found to be involved in monocyte arrest on atherosclerotic endothelium and may also play a pathophysiological role in Alzheimer’s disease.

GRO-α/KC/CXCL1 coded by CXCL1 gene at chromosome 5 is approximately 63% identity to that of mouse MIP2. KC is also approximately 60% identical to the human GROs. Mouse KC is a potent neutrophil attractant and activator. The functional receptor for KC has been identified as CXCR2. Based on the pattern of KC expression in a number of inflammatory disease models, KC appears to have an important role in inflammation. KC was found to be involved in monocyte arrest on atherosclerotic endothelium and may also play a pathophysiological role in Alzheimer’s disease.

GRO-α/KC/CXCL1 coded by CXCL1 gene at chromosome 5 is approximately 63% identity to that of mouse MIP2. KC is also approximately 60% identical to the human GROs. Mouse KC is a potent neutrophil attractant and activator. The functional receptor for KC has been identified as CXCR2. Based on the pattern of KC expression in a number of inflammatory disease models, KC appears to have an important role in inflammation. KC was found to be involved in monocyte arrest on atherosclerotic endothelium and may also play a pathophysiological role in Alzheimer’s disease.

Molecular Formula : C43H72Cl2P2Ru

Molecular Formula : C43H72Cl2P2Ru

Molecular Formula : C28 H32 Cl2 N2 Ru . C18 H33 P

Molecular Formula : C28 H32 Cl2 N2 Ru . C18 H33 P

Molecular Formula : C28 H32 Cl2 N2 Ru . C18 H33 P

Molecular Formula : C23H21N7O

GS96 broth delivers high yields of plasmid DNA in 96-well and 384-well plates

GS96 broth delivers high yields of plasmid DNA in 96-well and 384-well plates

Molecular Formula : C28H32Cl2N4O6S2

Molecular Formula : C28H32Cl2N4O6S2

Molecular Formula : C28H32Cl2N4O6S2

Molecular Formula : C25H17F2N5O3S

Molecular Formula : C25H17F2N5O3S

Molecular Formula : C24H20F3N5O

Molecular Formula : C24H20F3N5O

Molecular Formula : C28H28FN5O3

Molecular Formula : C28H28FN5O3

Molecular Formula : C28H28FN5O3

Molecular Formula : C27H28F3N5O2S

Molecular Formula : C27H28F3N5O2S

Molecular Formula : C22H22ClN5O2

Molecular Formula : C22H22ClN5O2

Molecular Formula : C22H22ClN5O2

Molecular Formula : C15H21N3O . HCl

Molecular Formula : C15H21N3O . HCl

Molecular Formula : C32H38ClN5O4

Molecular Formula : C32H38ClN5O4

Molecular Formula : C24 H19 F4 N5 O

Molecular Formula : C24 H19 F4 N5 O

Molecular Formula : C24 H19 F4 N5 O

Molecular Formula : C18H10Cl2N4OS

Molecular Formula : C31 H38 N6 O2

Molecular Formula : C31 H38 N6 O2

Molecular Formula : C31 H38 N6 O2

Molecular Formula : C22H22F3N3O3

Molecular Formula : C23H21FN6O

Molecular Formula : C17H17FN2O5

Molecular Formula : C17H17FN2O5

Molecular Formula : C17H17FN2O5

Glutathione Resin (Cat. No. L00206) is an affinity chromatography medium designed for easy, one-step purification of recombinant glutathione S-transferase (GST) fusion proteins and other glutathione binding proteins expressed in E. coli, insect cells and mammalian cells. The recombinant GST fusion proteins can be purified directly from pre-treated cell lysate using Glutathione Resin. It is the excellent choice for high performance purifications. 

GST Fusion Protein Purification Kit (Cat. No. L00207) is the derivate products of Glutathione Resin which includes five disposable columns and five 0.154 g samples of glutathione to facilitate protein purification.

GenScript GST tag ELISA Detection Kit is designed to quantitate glutathione-S-transferase (GST) or GST-fusion protein in samples such as cell lysate using a proprietary sandwich ELISA procedure in just 60 minutes. It utilizes two clones of GST monoclonal antibodies that bind to different epitopes of the GST tag protein at the same time. The GST monoclonal antibody, pre-coated on the plate, is used to capture GST tagged protein and the biotin conjugated GST monoclonal antibody (Biotin-GST Mab) is added to interact with GST tagged protein bound on the plate. Streptavidin-HRP is added to interact with Biotin-GST Mab and the final step involves the addition of TMB Substrate that will react with HRP to give product with an absorbance at 450 nm. The quantity of GST tagged protein in sample is determined by comparisons with the absorbance of that of a known GST tagged protein standard curve.

This antibody can be used to detect GST-fusion proteins in almost expression systems including bacterial expression system, mammalian expression system and other systems.

This antibody can be used to detect GST-fusion proteins in almost expression systems including bacterial expression system, mammalian expression system and other systems.

Guaiacol

Guaiacol