Ambient

Molecular Formula : C21 D5 H21 N2 O4

Molecular Formula : C21 D5 H21 N2 O4

Molecular Formula : C21 H26 N2 O4

Molecular Formula : C21 2H5 H23 N2 O5

Molecular Formula : C21 2H5 H23 N2 O5

Molecular Formula : C21H28N2O5

Molecular Formula : C119H156ClN21O40

Molecular Formula : C119H156ClN21O40

Molecular Formula : C119H156ClN21O40

Molecular Formula : C119H154ClN21O40 • x( C2H4O2)

Molecular Formula : C119H154ClN21O40 • x( C2H4O2)

Molecular Formula : C119H154ClN21O40 • x( C2H4O2)

Molecular Formula : C17 H17 N3 O . Cl H

Molecular Formula : C17 H17 N3 O . Cl H

Molecular Formula : C17 H17 N3 O . Cl H

Molecular Formula : C32H44N2O9

Molecular Formula : C32H44N2O9

Molecular Formula : C32H44N2O9

Molecular Formula : C10 H18 Cl N3 O7

Molecular Formula : C10 H18 Cl N3 O7

Molecular Formula : C10 H18 Cl N3 O7

Molecular Formula : C13 H22 N4 O3 S

Molecular Formula : C13 H22 N4 O3 S

Molecular Formula : C13 H22 N4 O3 S

Molecular Formula : C13 H22 N4 O3 S . Cl H

Molecular Formula : C13 H22 N4 O3 S . Cl H

Molecular Formula : C13 H22 N4 O3 S . Cl H

Molecular Formula : C13 H22 N4 O4 S

Molecular Formula : C13 H22 N4 O4 S

Molecular Formula : C13 H22 N4 O4 S

Molecular Formula : C13 H22 N4 O5 S

Molecular Formula : C13 H22 N4 O5 S

Molecular Formula : C13 2H6 H16 N4 O3 S

Molecular Formula : C13 2H6 H16 N4 O3 S

Molecular Formula : C13 2H6 H16 N4 O3 S

Molecular Formula : C13 2H6 H16 N4 O3 S . Cl H

Molecular Formula : C13 2H6 H16 N4 O3 S . Cl H

Molecular Formula : C13 2H6 H16 N4 O3 S . Cl H

Molecular Formula : C10H12D6N2OS

Molecular Formula : C10H12D6N2OS

Molecular Formula : C24 H33 N3 O4

Molecular Formula : C24 H33 N3 O4

Molecular Formula : C24 H33 N3 O4

Molecular Formula : C24H35Cl2N3O4

Molecular Formula : C24 2H3 H30 N3 O4

Molecular Formula : C24 2H3 H30 N3 O4

Molecular Formula : C24 2H3 H30 N3 O4

CCL5 or RANTES (acronym for Regulated upon Activation, Normal T cell Expressed and presumably Secreted), was initially discovered by subtractive hybridization as a transcript expressed in T cells but not B cells. Eosinophilchemotactic activities released by thrombinstimulated human platelets have also been purified and found to be identical to RANTES. Besides T cells and platelets, RANTES has been reported to be produced by renal tubular epithelium, synovial fibroblasts and selected tumor cells.

CCL5 or RANTES (acronym for Regulated upon Activation, Normal T cell Expressed and presumably Secreted), was initially discovered by subtractive hybridization as a transcript expressed in T cells but not B cells. Eosinophilchemotactic activities released by thrombinstimulated human platelets have also been purified and found to be identical to RANTES. Besides T cells and platelets, RANTES has been reported to be produced by renal tubular epithelium, synovial fibroblasts and selected tumor cells.

Chemokine (C-C motif) ligand 5(CCL5), also known as RANTES (Regulated upon activation, Normal T cell Expressed and presumable Secreted) is a CC-chemokine that can signal through the CCR1, CCR3, CCR5 and US28 (cytomegalovirus receptor) receptors. RANTES is chemotactic for T cells, eosinophils, and basophils, and plays an active role in recruiting leukocytes in inflammatory sites. With the help of specific cytokines (i.e., IL-2 and IFN-γ) that are released by T cells, RANTES induces the proliferation and activation of certain natural-killer (NK) cells to form CHAK (CC-Chemokine-activated killer) cells. RANTES is also an HIV-suppressive factor released from CD8+ T cells. This chemokine has been localized to chromosome 17 in humans. It has the capability to inhibit certain strains of HIV-1, HIV-2 and simian immunodeficiency virus (SIV).