Ambient

Molecular Formula : C27 H32 N4 O9

T cell immunoreceptor with Ig and ITIM domains (TIGIT) is an immune receptor present on some T cells and natural killer cells (NK). This protein could bind to CD155 (PVR) with high affinity, which causes increased secretion of IL-10 and decreased secretion of IL-12B and suppresses T-cell activation by promoting the generation of mature immunoregulatory dendritic cells. TIGIT could also bind to CD112 (PVRL2) with lower affinity. TIGIT’s inhibition of NK cytotoxicity can be blocked by antibodies against its interaction with PVR and the activity is directed through its ITIM domain.

T cell immunoreceptor with Ig and ITIM domains (TIGIT) is an immune receptor present on some T cells and natural killer cells (NK). This protein could bind to CD155 (PVR) with high affinity, which causes increased secretion of IL-10 and decreased secretion of IL-12B and suppresses T-cell activation by promoting the generation of mature immunoregulatory dendritic cells. TIGIT could also bind to CD112 (PVRL2) with lower affinity. TIGIT’s inhibition of NK cytotoxicity can be blocked by antibodies against its interaction with PVR and the activity is directed through its ITIM domain.

T cell immunoreceptor with Ig and ITIM domains (TIGIT) is an immune receptor present on some T cells and natural killer cells (NK). This protein could bind to CD155 (PVR) with high affinity, which causes increased secretion of IL-10 and decreased secretion of IL-12B and suppresses T-cell activation by promoting the generation of mature immunoregulatory dendritic cells. TIGIT could also bind to CD112 (PVRL2) with lower affinity. TIGIT’s inhibition of NK cytotoxicity can be blocked by antibodies against its interaction with PVR and the activity is directed through its ITIM domain.

Molecular Formula : C5 H8 O2

Molecular Formula : C12H14O2

Molecular Formula : C12H14O2

Molecular Formula : C5 2H3 H5 O2

Molecular Formula : C5 2H3 H5 O2

Molecular Formula : C5 H7 Cl O

Molecular Formula : C5 H7 Cl O

Molecular Formula : C5 H7 Cl O

Molecular Formula : C7 H11 N O3

Molecular Formula : C7 H11 N O3

Molecular Formula : C7 H11 N O3

Molecular Formula : 13C2 C5 H11 15N O3

Molecular Formula : 13C2 C5 H11 15N O3

Molecular Formula : 13C2 C6 H13 15N O3

Molecular Formula : 13C2 C6 H13 15N O3

Molecular Formula : 13C2 C6 H13 15N O3

Molecular Formula : C12H22ClNO4

Molecular Formula : C12H22ClNO4

Molecular Formula : C12H18D3NO4

Molecular Formula : C12H18D3NO4

Molecular Formula : C27H44O3

Molecular Formula : C27H44O3

Molecular Formula : C27H44O3

Molecular Formula : C10H8BrNO

Molecular Formula : C10H8BrNO

Molecular Formula : C41 H71 N3 O8

Molecular Formula : C41 H71 N3 O8

Molecular Formula : C41 H71 N3 O8

Molecular Formula : C41H61D10N3O8

Molecular Formula : C41H61D10N3O8

Molecular Formula : C17 H23 N O2 . Cl H

Molecular Formula : C17 H23 N O2 . Cl H

Molecular Formula : C13 H19 N O2 . Cl H

Molecular Formula : C13 H19 N O2 . Cl H

Molecular Formula : C13 H19 N O2 . Cl H

Molecular Formula : C17 2H6 H17 N O2 . Cl H

Molecular Formula : C17 2H6 H17 N O2 . Cl H

Molecular Formula : C20H19N3O2

Molecular Formula : C20H19N3O2

Molecular Formula : C46 H80 N2 O13 . H3 O4 P

Molecular Formula : C46 H80 N2 O13 . H3 O4 P

Molecular Formula : C46 H80 N2 O13 . H3 O4 P

Molecular Formula : C46H77D3N2O13

Molecular Formula : C46H77D3N2O13

Molecular Formula : C46H77D3N2O13