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Owl Replacement Gasket Set of 2

Owl Replacement Gasket Set of 2

Owl Replacement Gasket Set of 2

Owl Replacement Gasket Set of 2

Owl Replacement Gasket Set of 2

Owl Replacement Gasket, pkg 2

Owl Replacement Knot for Penguin, PK of 4

Owl Replacement Lid

Owl S3S Replacement Clamp

Owl Side Clamps, pkg 2

Owl Side clamps, pkg 2

Owl Spacer Set (3), 45 x 1 cm, 0.4 mm thick

Owl Spacer set (3), 45 x 1 cm, 0.4 mm thick

Owl Spacer set, 0.8mm thick

Owl Spacer set, 0.8mm thick

Owl Spacer set, 1 cm Width, 0.8 mm Thick

Owl Spacer set, 1 cm Width, 1.5 mm Thick

Owl Spacer set, 1.5mm thick

Owl Stainless Steel Binder clamps, dozen

Owl Stopcock, pkg. 2

Owl Super Safe Lid with Attached Power Supply Leads for P8DS

Owl The Stretch Otter(TM) sequencing gel caster

Owl Transfer Membrane, Roll, 26.5 x 3.75 cm

Owl Transfer Membrane, Sheets, 10 x 10 cm, 10/pk

Owl Transfer Membrane, Sheets, 15 x 15 cm, 10/pk

Owl Upper Buffer Chamber Only

Owl UVT gel tray

Owl UVT gel tray, 23 x 40 cm

Owl Vertical Gel Wedge System Double Sided 10 x 10 cm

Owl Wall Comb. 1.5 mm thick

Owl Wall Comb. 1.5 mm thick

Owl Water cooled complete system plus caster, 20 x 20 cm

Owl Water cooled complete system, 20 x 20 cm

Owl Water cooled system apparatus only, 20 x 20 cm

Owl Water Cooled System, Apparatus Only, 10 x 10 cm

Owl Water Cooled System, Complete System Plus Caster 10 x 10 cm

Owl Water Cooled System, Complete System, 10 x 10 cm

Owl Wedge Spacer Set (2), 0.4 – 0.8 mm Thick

Owl Wing Knob for P81 Vertical Electrophoresis System

OX40 (TNFRSF4, CD134) is a member of the tumor necrosis factor (TNF) receptor superfamily that regulates T cell activity and immune responses. The OX40 protein contains four cysteine rich domains, a transmembrane domain, and a cytoplasmic tail containing a QEE motif. OX40 is primarily expressed on activated CD4+ and CD8+ T-cells, while the OX40 ligand (OX40L, TNFSF4, CD252) is predominantly expressed on activated antigen presenting cells. The engagement of OX40 with OX40L leads to the recruitment of TNF receptor-associated factors (TRAFs) and results in the formation of a TCR-independent signaling complex. One component of this complex, PKCθ, activates the NF-κB pathway. OX40 signaling through Akt can also enhance TCR signaling directly. Research studies indicate that the OX40L-OX40 pathway is associated with inflammation and autoimmune diseases. Additional research studies show that OX40 agonists augment anti-tumor immunity in several cancer types.

OX40 (TNFRSF4, CD134) is a member of the tumor necrosis factor (TNF) receptor superfamily that regulates T cell activity and immune responses. The OX40 protein contains four cysteine rich domains, a transmembrane domain, and a cytoplasmic tail containing a QEE motif. OX40 is primarily expressed on activated CD4+ and CD8+ T-cells, while the OX40 ligand (OX40L, TNFSF4, CD252) is predominantly expressed on activated antigen presenting cells. The engagement of OX40 with OX40L leads to the recruitment of TNF receptor-associated factors (TRAFs) and results in the formation of a TCR-independent signaling complex. One component of this complex, PKCθ, activates the NF-κB pathway. OX40 signaling through Akt can also enhance TCR signaling directly. Research studies indicate that the OX40L-OX40 pathway is associated with inflammation and autoimmune diseases. Additional research studies show that OX40 agonists augment anti-tumor immunity in several cancer types.

OX40 is a T cell co-stimulatory molecule of the TNF receptor superfamily that coordinates with other co-stimulators (CD28, CD40, CD30, CD27 and 4-1BB) to manage the activation of the immune response. Tumor necrosis factor ligand superfamily member 4 (TNFSF4) is also known as glycoprotein Gp34, OX40 ligand (OX40L), TAX transcriptionally-activated glycoprotein 1 and CD252, which belongs to the tumor necrosis factor family. TNFSF4 is the ligand for CD134 and is expressed on cells such as DC2s (a subtype of dendritic cells) enabling amplification of Th2 cell differentiation. OX40 is constitutively expressed on Tregs and enhances the sensitivity of Tregs to IL-2, thus promoting Treg proliferation. OX40 has also shown to decrease the cells’ immunosuppressive activity on effector T cells. OX40-OX40 Ligand signaling is involved in allergic airway inflammation, graft-versus-host disease and autoimmune disease.

OX40 is a T cell co-stimulatory molecule of the TNF receptor superfamily that coordinates with other co-stimulators (CD28, CD40, CD30, CD27 and 4-1BB) to manage the activation of the immune response. Tumor necrosis factor ligand superfamily member 4 (TNFSF4) is also known as glycoprotein Gp34, OX40 ligand (OX40L), TAX transcriptionally-activated glycoprotein 1 and CD252, which belongs to the tumor necrosis factor family. TNFSF4 is the ligand for CD134 and is expressed on cells such as DC2s (a subtype of dendritic cells) enabling amplification of Th2 cell differentiation. OX40 is constitutively expressed on Tregs and enhances the sensitivity of Tregs to IL-2, thus promoting Treg proliferation. OX40 has also shown to decrease the cells’ immunosuppressive activity on effector T cells. OX40-OX40 Ligand signaling is involved in allergic airway inflammation, graft-versus-host disease and autoimmune disease.

Polyclonal Antibodies

Polyclonal Antibodies

Tumor necrosis factor ligand superfamily member 4 (TNFSF4) is also known as glycoprotein Gp34, OX40 ligand (OX40L), which belongs to the tumor necrosis factor family. It is expressed on such cells as DC2s (a subtype of dendritic cells) enabling amplification of Th2 cell differentiation.

Polyclonal Antibodies

Polyclonal Antibodies