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DNAM-1 (DNAX accessory molecule-1), also known as CD226, platelet and T cell activation antigen 1 (PTA1) and TLiSA1, is a member of the Ig superfamily containing two Ig-like domains of the V set and is encoded by a gene on human chromosome 18q22.3. DNAM-1 is an activating receptor expressed on natural killer (NK) cells, CD8+ T cells, and other immune cells. Upon recognition of its ligands, CD155 and CD112, DNAM-1 promotes NK cell–mediated elimination of transformed and virus-infected cells. It also has a key role in expansion and maintenance of virus-specific memory NK cells. DNAM-1 is the cell surface receptor of NECTIN2. Upon ligand binding, it stimulates T cell proliferation and cytokine production, including that of IL2, IL5, IL10, IL13 and IFNG.

DNAM-1 (DNAX accessory molecule-1), also known as CD226, platelet and T cell activation antigen 1 (PTA1) and TLiSA1, is a member of the Ig superfamily containing two Ig-like domains of the V set and is encoded by a gene on human chromosome 18q22.3. DNAM-1 is an activating receptor expressed on natural killer (NK) cells, CD8+ T cells, and other immune cells. Upon recognition of its ligands, CD155 and CD112, DNAM-1 promotes NK cell–mediated elimination of transformed and virus-infected cells. It also has a key role in expansion and maintenance of virus-specific memory NK cells. DNAM-1 is the cell surface receptor of NECTIN2. Upon ligand binding, it stimulates T cell proliferation and cytokine production, including that of IL2, IL5, IL10, IL13 and IFNG.

DNAM-1 (DNAX accessory molecule-1), also known as CD226, platelet and T cell activation antigen 1 (PTA1) and TLiSA1, is a member of the Ig superfamily containing two Ig-like domains of the V set and is encoded by a gene on human chromosome 18q22.3. DNAM-1 is an activating receptor expressed on natural killer (NK) cells, CD8+ T cells, and other immune cells. Upon recognition of its ligands, CD155 and CD112, DNAM-1 promotes NK cell–mediated elimination of transformed and virus-infected cells. It also has a key role in expansion and maintenance of virus-specific memory NK cells. DNAM-1 is the cell surface receptor of NECTIN2. Upon ligand binding, it stimulates T cell proliferation and cytokine production, including that of IL2, IL5, IL10, IL13 and IFNG.

CD226 (Cluster of Differentiation 226), also known as PTA1 (outdated term, ‘platelet and T cell activation antigen 1’)[5] or DNAM-1 (DNAX Accessory Molecule-1), is a ~65 kDa glycoprotein expressed on the surface of natural killer cells, platelets, monocytes and a subset of T cells. It is a member of the immunoglobulin superfamily. This protein is involved in intercellular adhesion, lymphocyte signaling, cytotoxicity and lymphokine secretion mediated by cytotoxic T-lymphocyte (CTL) and NK cell. It is the cell surface receptor for NECTIN2 and its main ligands are CD112 and CD155. It stimulates T-cell proliferation and cytokine production, including that of IL-2, IL-5, IL-10, IL-13, and IFNγ upon ligand binding.

CD226 (Cluster of Differentiation 226), also known as PTA1 (outdated term, ‘platelet and T cell activation antigen 1’)[5] or DNAM-1 (DNAX Accessory Molecule-1), is a ~65 kDa glycoprotein expressed on the surface of natural killer cells, platelets, monocytes and a subset of T cells. It is a member of the immunoglobulin superfamily. This protein is involved in intercellular adhesion, lymphocyte signaling, cytotoxicity and lymphokine secretion mediated by cytotoxic T-lymphocyte (CTL) and NK cell. It is the cell surface receptor for NECTIN2 and its main ligands are CD112 and CD155. It stimulates T-cell proliferation and cytokine production, including that of IL-2, IL-5, IL-10, IL-13, and IFNγ upon ligand binding.

CD226 (Cluster of Differentiation 226), also known as PTA1 (outdated term, ‘platelet and T cell activation antigen 1’)[5] or DNAM-1 (DNAX Accessory Molecule-1), is a ~65 kDa glycoprotein expressed on the surface of natural killer cells, platelets, monocytes and a subset of T cells. It is a member of the immunoglobulin superfamily. This protein is involved in intercellular adhesion, lymphocyte signaling, cytotoxicity and lymphokine secretion mediated by cytotoxic T-lymphocyte (CTL) and NK cell. It is the cell surface receptor for NECTIN2 and its main ligands are CD112 and CD155. It stimulates T-cell proliferation and cytokine production, including that of IL-2, IL-5, IL-10, IL-13, and IFNγ upon ligand binding.

DNAPac PA200 8 um, 2 x 250 mm Analytical Column

DNAPac PA200 8 um, 4 x 200 mm Analytical Column

Deoxyribonuclease
I (DNase I) is DNA-specific endonuclease that cleaves both single-stranded DNA,double-stranded
DNA and DNA-RNA hybrids, yielding 5′-phosphate-terminated polynucleotides with
a free hydroxyl group on position 3′ producing tetranucleotides. The activity of DNase I is strictly
dependent on Ca²⁺ and can be activated by divalent metal ions such
as Mg²⁺ or Mn²⁺. In the presence of Mg²⁺,
DNase I nonspecifically recognizes and cleaves a double-stranded DNA at anysite
on either strand, and in the presence of Mn²⁺, it recognizes and
cleaves almost the same sites on both strands of the DNA to produce DNA
fragments with blunt ends or sticky ends with 1~2 nucleotide overhangs.

GenScript is
offering DNase I produced by expression in a P. pastoris strain carrying a plasmid encoding the bovine DNase I.

Deoxyribonuclease
I (DNase I) is DNA-specific endonuclease that cleaves both single-stranded DNA,double-stranded
DNA and DNA-RNA hybrids, yielding 5′-phosphate-terminated polynucleotides with
a free hydroxyl group on position 3′ producing tetranucleotides. The activity of DNase I is strictly
dependent on Ca²⁺ and can be activated by divalent metal ions such
as Mg²⁺ or Mn²⁺. In the presence of Mg²⁺,
DNase I nonspecifically recognizes and cleaves a double-stranded DNA at anysite
on either strand, and in the presence of Mn²⁺, it recognizes and
cleaves almost the same sites on both strands of the DNA to produce DNA
fragments with blunt ends or sticky ends with 1~2 nucleotide overhangs.

GenScript is
offering DNase I produced by expression in a P. pastoris strain carrying a plasmid encoding the bovine DNase I.

Deoxyribonuclease
I (DNase I) is DNA-specific endonuclease that cleaves both single-stranded DNA,double-stranded
DNA and DNA-RNA hybrids, yielding 5′-phosphate-terminated polynucleotides with
a free hydroxyl group on position 3′ producing tetranucleotides. The activity of DNase I is strictly
dependent on Ca²⁺ and can be activated by divalent metal ions such
as Mg²⁺ or Mn²⁺. In the presence of Mg²⁺,
DNase I nonspecifically recognizes and cleaves a double-stranded DNA at anysite
on either strand, and in the presence of Mn²⁺, it recognizes and
cleaves almost the same sites on both strands of the DNA to produce DNA
fragments with blunt ends or sticky ends with 1~2 nucleotide overhangs.

GenScript is
offering DNase I produced by expression in a P. pastoris strain carrying a plasmid encoding the bovine DNase I.

Molecular/Enzyme Products

Molecular/Enzyme Products

Molecular/Enzyme Products

Molecular/Enzyme Products

Consumable

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Polyclonal Antibodies

Polyclonal Antibodies

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Polyclonal Antibodies

Polyclonal Antibodies

DNASwift SAX-1S 5 x 150 mm Analytical Column

Polyclonal Antibodies

Polyclonal Antibodies

Polyclonal Antibodies

Polyclonal Antibodies

Polyclonal Antibodies

Polyclonal Antibodies

Polyclonal Antibodies

Polyclonal Antibodies

Polyclonal Antibodies

Polyclonal Antibodies

Polyclonal Antibodies

Polyclonal Antibodies

Polyclonal Antibodies

Polyclonal Antibodies

Monoclonal Antibodies

Monoclonal Antibodies

Polyclonal Antibodies

Polyclonal Antibodies

Polyclonal Antibodies

Polyclonal Antibodies

Polyclonal Antibodies

Polyclonal Antibodies

Polyclonal Antibodies

Polyclonal Antibodies