2

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the virus that causes coronavirus disease 2019 (COVID-19), the respiratory illness responsible for the COVID-19 pandemic. SARS-CoV-2 also known as 2019-nCoV, is a positive-sense single-stranded RNA virus and is believed to have zoonotic origins and has close genetic similarity to bat coronaviruses. The receptor binding domain (RBD) of spike protein of the SARS-CoV-2 virus binds Angiotensin-Converting Enzyme 2 (ACE2) to invade the host cells. Based on structural biology studies, the RBD can be oriented either in the up/standing or down/lying state with the up/standing state associated with higher pathogenicity.

SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2) also known as 2019-nCoV (2019 Novel Coronavirus) is a virus that causes illnesses ranging from the common cold to severe diseases. As of May 2021, three sublineages have been found. Despite its name, B.1.617.3 was the first sublineage of this variant to be detected, in October 2020 in India. This sublineage has remained relatively uncommon compared to the two other sublineages, B.1.617.1 (also known as variant Kappa) and B.1.617.2 (also known as variant Delta), both of which were first detected in December 2020. This variant has the double mutations E484Q and L452R in the spike proteins. Emerging research suggests the variant may be more transmissible than previously evolved ones. Whether the effectiveness of currently-deployed vaccines is affected remains under investigation. Moreover, the sublineage B.1.617.2 has been redesignated as “variant of concern” (VOC-21APR-02) in May 2021, which spreads more quickly than the original version of the virus.

BA.2 differs from BA.1 in its genetic sequence, including some amino acid differences in the spike protein and other proteins. Studies have shown that BA.2 has a growth advantage over BA.1. Studies are ongoing to understand the reasons for this growth advantage, but initial data suggest that BA.2 appears inherently more transmissible than BA.1, which currently remains the most common Omicron sublineage reported. This difference in transmissibility appears to be much smaller than, for example, the difference between BA.1 and Delta. Further, although BA.2 sequences are increasing in proportion relative to other Omicron sublineages (BA.1 and BA.1.1), there is still a reported decline in overall cases globally.

SARS-CoV-2 (Severe Acute Respiratory
Syndrome Coronavirus 2) also known as 2019-nCoV (2019 Novel Coronavirus) is a virus that causes illnesses ranging from the common cold to severe diseases. Recently, the new B.1.1.529 variant was confirmed in South Africa and preliminary evidence suggests an increased risk of reinfection with this variant. The B.1.1.529 variant was first reported to WHO on 24 November 2021 and WHO has designated this variant as a VOC (Variant of Concern), named Omicron. There are more than 30 mutations in the spike protein.

SCILOGEX Square Cuvettes, Quartz, 10 mm, 4.5 ml capacity

Sealed Microplate Buckets for M10 Swinging Bucket Rotor (487-10154)

Separatory Funnels, Borosilicate Glass, PTFE stopcock, Plastic stopper, 100 mL

Separatory Funnels, Borosilicate Glass, PTFE stopcock, Plastic stopper, 125 mL

Separatory Funnels, Borosilicate Glass, PTFE stopcock, Plastic stopper, 125 mL

Separatory Funnels, Borosilicate Glass, PTFE stopcock, Plastic stopper, 250 mL

Separatory Funnels, Borosilicate Glass, PTFE stopcock, Plastic stopper, 250 mL

Separatory Funnels, Borosilicate Glass, PTFE stopcock, Plastic stopper, 50 mL

Separatory Funnels, Borosilicate Glass, PTFE stopcock, Plastic stopper, 500 mL

SIBATA Class A Glass Graduated Cylinder, To Contain, 1000 mL

SIBATA Class A Glass Graduated Cylinder, To Contain, 1000 mL

SIBATA Class A Glass Graduated Cylinder, To Contain, 500 mL

SIBATA Class A Glass Graduated Cylinder, To Contain, 500 mL

SIBATA Class A Volumetric Flasks with Snap Cap, To Contain, 1000 mL

SIBATA Class A Volumetric Flasks with Snap Cap, To Contain, 1000 mL

SIBATA Class A Volumetric Flasks with Snap Cap, To Contain, 500 mL

SIBATA Class A Volumetric Flasks with Snap Cap, To Contain, 500 mL

Sibata Low-Actinic, Class A, Amber Glass Volumetric Flasks, 1000 ml

Sibata Low-Actinic, Class A, Amber Glass Volumetric Flasks, 1000 ml

Sibata Low-Actinic, Class A, Amber Glass Volumetric Flasks, 500 ml

Sibata Low-Actinic, Class A, Amber Glass Volumetric Flasks, 500 ml

Single large bottle holder up to 4.5 diameter, 1/4 in. clear PETG, 6W x 5.5H x 6D

SmartCheck Tri-color Extended Range Plus Protein Marker, 13 bands 9-245 kDa, 2 x 250 uL

SmartCheck Tri-color Protein Marker, 10 bands 9-180 kDa, 2 x 250 uL