0.5mg

Molecular Formula : C36H30D8N4O8

Molecular Formula : C21 2H4 H26 O5

Molecular Formula : C21H25D4KO8S

Molecular Formula : C27 H31 O15 . Cl

Molecular Formula : C43 H49 N4 Na O14 S2

Molecular Formula : C34H44KN3O9S4

Molecular Formula : C37H45KN2O10S2

Molecular Formula : C36 H46 K N3 O9 S4

Molecular Formula : C30 H50 O

Molecular Formula : 13C2 C60 D4 H107 N11 O12

Molecular Formula : C63 H111 N11 O13

Molecular Formula : C4 13C5 H16 N3 O14 P3 • x(Et3N)

Molecular Formula : C29H35N05

Molecular Formula : C25 2H3 H22 N7 O3

Molecular Formula : C25H18D7N7O3

Molecular Formula : C22H18D8ClN7O3S

Molecular Formula : C15 H20 O5

Molecular Formula : C42 H28 N6 O9 S

Molecular Formula : C25 D7 H41 N6 O8 . x(C2 H F3 O2)

Molecular Formula : C29 H48 O

Molecular Formula : C18 H28 N4 O7 . H Cl

Molecular Formula : C29 H33 N3 O4

Molecular Formula : C28 H20 Cl2 F6 N2 O4

Molecular Formula : C16 H22 N4 O7 S

The GenCRISPR™
SaCas9 2NLS Nuclease can be formed with the guide RNA into a ribonucleoprotien
(RNP) complex. The use of an RNP complex to perform gene editing has been shown
to reduce the challenges encountered with other CRISPR gene editing techniques
such as viral and plasmid delivery. Challenges include off-target effects, cell
viability and transcription/translational challenges. The SaCas9 recognizes an
NNGRRT protospacer adjacent motif (PAM) and cleaves target DNA at high
efficiency with a variety of guide RNA (gRNA) spacer lengths.

GenCRISPR™ SaCas9 2NLS
Nuclease is a tag free nuclease produced by expression in an E. coli strain carrying a plasmid
encoding the Cas9 gene from Staphylococcus
aureus with a nuclear localization signal at both N-terminal and C-terminal.The
small size of the nuclease facilitates enhanced in vivo delivery for genome
editing in various organisms.

The GenCRISPR™
Ultra eSpCas9 product line provides customers with a selection of research use,
basic GMP and GMP compliant Cas9 nucleases. The Cas9 protein can be formed with
the guide RNA into a ribonucleoprotien (RNP) complex. The use of an RNP complex
to perform gene editing has been shown to reduce the challenges encountered
with other CRISPR gene editing techniques such as viral and plasmid delivery.
Challenges include off-target effects, cell viability and transcription/translational
challenges.

GenCRISPR™
Ultra eSpCas9-2NLS is a mutant form of Cas9 nuclease and is produced by
expression in an E. coli strain
carrying a plasmid encoding the eSpCas9 gene from Streptococcus pyogenes with double-ended nuclear localization
signal (NLS). GenCRISPR™ Ultra eSpCas9-2NLS delivers higher fidelity and less
off-target activity than wild-type SpCas9 nuclease.

The GenCRISPR™
Ultra eSpCas9 product line provides customers with a selection of research use,
basic GMP and GMP compliant Cas9 nucleases. The Cas9 protein can be formed with
the guide RNA into a ribonucleoprotien (RNP) complex. The use of an RNP complex
to perform gene editing has been shown to reduce the challenges encountered
with other CRISPR gene editing techniques such as viral and plasmid delivery.
Challenges include off-target effects, cell viability and transcription/translational
challenges.

GenCRISPR™ Ultra eSpCas9-N-NLS
Research, tag-free is a mutant form of Cas9
nuclease and is produced by expression in an E. coli strain carrying a plasmid encoding the eSpCas9 gene from Streptococcus pyogenes with an N-terminal
nuclear localization signal (N-NLS). GenCRISPR™ Ultra eSpCas9-N-NLS Research,
tag-free delivers higher fidelity
and less off-target activity than wild-type SpCas9 nuclease.

The
GenCRISPR™ Ultra Cas9 product line provides customers with a selection of
research use, GMP preclinical and GMP compliant Cas9 nucleases. The Cas9
protein can be formed with the guide RNA into a ribonucleoprotien (RNP)
complex. The use of an RNP complex to perform gene editing has been shown to
reduce the challenges encountered with other CRISPR gene editing techniques
such as viral and plasmid delivery. Challenges include off-target effects, cell
viability and trascprition/translational challenges.

GenCRISPR™ Ultra Cas9 is
produced by expression in an E. coli
strain carrying a plasmid encoding the Cas9 gene from Streptococcus pyogenes with an N-terminal nuclear localization
signal (NLS).

Molecular Formula : 13C4H815N2O3 H2O

Molecular Formula : C6 2H6 H7 N3 O3

Molecular Formula : C14 H22 N2 O

Molecular Formula : C17H11D5KNO5S

Molecular Formula : C9H9NO2

Molecular Formula : C18 H22 N2 O

Molecular Formula : C14 D4 H14 N2 O5

Molecular Formula : C23 H23 N9 O4

Molecular Formula : C₂₈H₃₈D₅FN₃O₉PSi

Molecular Formula : C14 D6 H10 N2 O3

Molecular Formula : C13H23Cl3N4O6

Molecular Formula : C10 H13 Cl F N5 O4

Molecular Formula : C12 D3 H11 N2 O2

Molecular Formula : C213C3H915NO3S

Molecular Formula : C5H6D3NO4

Molecular Formula : C20H32D3N3O4S

Molecular Formula : C513C4H17NO5S

Molecular Formula : C613C6H15NO3S

Molecular Formula : C51H67D7N6O10

Molecular Formula : C23H43NO4

Molecular Formula : C19 D4 H22 N2 O7

Molecular Formula : C16 D4 H9 N3 O3