1mg

Molecular Formula : C36H38D3N3O6

Molecular Formula : C36D3H38N3O6.HCl

Molecular Formula : C26 H21 N3 O4

Molecular Formula : C17D4H7N5

Molecular Formula : C39H65NO14

Molecular Formula : C59H74D10N16O12 • x(C2HF3O2)

Molecular Formula : C59H79D5N16O12• x(C2H4O2)

Molecular Formula : 2 C46 H56 N4 O9 . H2 O4 S

Molecular Formula : C9 H10 D3 N . H Cl

Molecular Formula : C11 D5 H7 N2 S . H Cl

Molecular Formula : C8H11D3N2O2

Molecular Formula : C8 2H6 H8 N2 O2

Molecular Formula : C8 D6 H8 N2 O2

Molecular Formula : C19 H24 N2 O S . C4 H4 O4

Molecular Formula : C19H21D3N2OS

Molecular Formula : C18 H21 F2 N3 O4

Molecular Formula : C18H17D3FN3O4

Molecular Formula : C18H16D3FN3NaO4

Molecular Formula : C18H12D8FN3O4

Molecular Formula : 13C C19 2H3 H22 N7 O6

Molecular Formula : No Data Available

Molecular Formula : C21H21I4NO9

Molecular Formula : C27 H31 I4 N O14

Molecular Formula : C20 H35 N O15

Molecular Formula : C49 H61 N O15

Molecular Formula : C20 H35 N O15

Molecular Formula : C30 H41 N O17

Molecular Formula : C26 H45 N O19

Molecular Formula : C16 H14 Cl F3 N2 O

Molecular Formula : C23 H22 Cl N O2

Molecular Formula : C14 2H10 H12 N2 O

Molecular Formula : C14H17D6ClN2O

Molecular Formula : C37H42N2O6

Leukemia Inhibitory Factor (LIF) is a pleiotropic cytokine belonging to the long four-helix bundle cytokine superfamily. LIF shares tertiary structure with several other cytokines, including Interleukin-6 (IL-6), Oncostatin M, ciliary neurotropic factor, and cardiotrophin-1, and their functions in vivo are also redundant to some extent. LIF can bind to the common receptor of IL-6 subfamily, gp130, and then recruit its own receptor LIF Receptor to form a ternary complex. The basal expression of LIF in vivo is low; and its expression is induced by pro-inflammatory factors, including lipopolysaccharide, IL-1, and IL-17, and inhibited by anti-inflammatory agents, including IL-4 and IL-13. The functions of LIF include proliferation of primordial germ cells, regulation in blastocyst implantation and early pregnancy, and maintenance of pluripotent embryonic stem cells.

Leukemia Inhibitory Factor (LIF) is a pleiotropic cytokine belonging to the long four-helix bundle cytokine superfamily. LIF shares tertiary structure with several other cytokines, including Interleukin-6 (IL-6), Oncostatin M, ciliary neurotropic factor, and cardiotrophin-1, and their functions in vivo are also redundant to some extent. LIF can bind to the common receptor of IL-6 subfamily, gp130, and then recruit its own receptor LIF Receptor to form a ternary complex. The basal expression of LIF in vivo is low; and its expression is induced by pro-inflammatory factors, including lipopolysaccharide, IL-1, and IL-17, and inhibited by anti-inflammatory agents, including IL-4 and IL-13. The functions of LIF include proliferation of primordial germ cells, regulation in blastocyst implantation and early pregnancy, and maintenance of pluripotent embryonic stem cells.

LIGHT, also known as tumor-necrosis factor (TNF) superfamily member 14 (TNFSF14), is predominantly expressed on activated immune cells and some tumor cells. LIGHT (homologous to lymphotoxin, exhibits inducible expression and competes with Herpes Simplex Virus glycoprotein D for Herpes Virus Entry Mediator, a receptor expressed by T cells), is a protein primarily expressed on activated T cells, activated Natural Killer (NK) cells, and immature dendritic cells (DC). LIGHT can function as both a soluble and cell surface-bound type II membrane protein and must be in its homotrimeric form to interact with its two primary functional receptors: Herpes Virus Entry Mediator (HVEM) and Lymphotoxin-β Receptor (LTβR). LIGHT signaling through these receptors have distinct functions that are cell-type dependent, but interactions with both types of receptors have immune-related implications in tumor biology.

Molecular Formula : C12 H14 O2

Molecular Formula : C22 H36 O5

Molecular Formula : C17 H14 Cl2 F2 N4 O S

Molecular Formula : C27 D3 H27 N8 O3

Molecular Formula : C51 H56 N16 O4

Molecular Formula : C50H56N16O4

Molecular Formula : C25 D3 H25 N8 O2

Molecular Formula : C10 H18 O2

Molecular Formula : C18H35N2O9PS

Molecular Formula : C17H32N2O6S

Molecular Formula : C17H33ClN2O6S

Molecular Formula : C35H51N11O9S2. x C2F3OOH

Molecular Formula : C21 H18 F N5 O

Molecular Formula : C172H265N43O51