1mg

Molecular Formula : C20 H26 N4 O4

Molecular Formula : C21 H18 D7 N . H Cl

Molecular Formula : C9 D10 H11 O2 P S3

Molecular Formula : C9 H21 O5 P S2

Molecular Formula : C9 H21 O4 P S2

Molecular Formula : C12H10D9NO3

Molecular Formula : 13C8 H6 O4

Molecular Formula : C12 2H4 H5 F3 N2 O2

Molecular Formula : C181D10H281N55O51S2

Molecular Formula : C56H77D5N16O19S2

Molecular Formula : C7H6D6ClN3O3

Molecular Formula : C19 H20 F N3 O2 S

Molecular Formula : C15 D7 H23 N2 O3

Molecular Formula : C25H34FN3O6S

Molecular Formula : C25 H34 O4

Molecular Formula : C20 H24 O7 S

Molecular Formula : C17 H23 Cl2 N O

Molecular Formula : C19 H26 O3

Testosterone
is an important sex hormone in males. It is synthesized in the body from
cholesterol. Testosterone is critical for the development of male
reproductive tissues. It also regulates sexual development and red blood cell
production.

Testosterone
is an important sex hormone in males. It is synthesized in the body from
cholesterol. Testosterone is critical for the development of male
reproductive tissues. It also regulates sexual development and red blood cell
production.

Molecular Formula : C25 H35 O8 . Na

Molecular Formula : C27 D3 H37 O3

Molecular Formula : C26H37D3O3

Molecular Formula : C25H40D3NO5S

Molecular Formula : C30H45D3O3

Molecular Formula : C19 2H5 H23 O2

Molecular Formula : C25H32D3NaO8

Molecular Formula : C22 2H3 H29 O3

Molecular Formula : C26H29D3I3N3O12

Molecular Formula : C19H21D6NO3

Molecular Formula : 13C12 C3 H12 Br4 O2

Molecular Formula : 13C6 C2 H2 Br4 O4

Molecular Formula : C27H42O9

Molecular Formula : C21H26D6O5

Molecular Formula : C21H18D6O6

Molecular Formula : C13H12D4N2 • HCl

Molecular Formula : C19 D6 H18 O2

Molecular Formula : C6D12N2S3

Molecular Formula : C11 H17 N3 O8

Molecular Formula : C34H33N3O6S2

Molecular Formula : C34 H37 N3 O8 S4

Molecular Formula : C26 H27 F3 N2 O6

The Trefoil Factor peptides (TFF1, TFF2 and TFF3) are secreted in the gastrointestinal tract, and appear to play an important role in intestinal mucosal defense and repair. TFF-3 is expressed by goblet cells and in the uterus, and has also been shown to express in certain cancers, including colorectal, hepatocellular, and in biliary tumors. TFF3 may be useful as a molecular marker for certain types of cancer, but its role, if any, in tumorigenesis is unknown. TFF3 also promotes airway epithelial cell migration and differentiation.

Transforming Growth Factor-alpha (TGF-α) , also known as sarcoma growth factor, TGF-type I and ETGF, is a member of the EGF family of cytokines. It is expressed in monocytes, brain cells, keratinocytes and various tumor cells. TGF-α signals through EGFR and acts synergistically with TGF-beta to promote the proliferation of a wide range of epidermal and epithelial cells. TGF-α is a transforming growth factor that is a ligand for the epidermal growth factor receptor, which activates a signaling pathway for cell proliferation, differentiation and development. This protein may act as either a transmembrane-bound ligand or a soluble ligand. The biological actions of TGF-α and EGF are similar. For instance, TGF-α and EGF bind to the same receptor. When TGF-α binds to EGFR it can initiate multiple cell proliferation events.

Transforming growth factor beta 1 (TGFβ1) is the prototype of a growing superfamily of peptide growth factors and plays a prominent role in a variety of cellular processes, including cell-cycle progression, cell differentiation, reproductive function, development, motility, adhesion, neuronal growth, bone morphogenesis, wound healing, and immune surveillance. TGF-β1, TGF-β2 and TGF-β3 signal via the same heteromeric receptor complex, consisting of a ligand binding TGF-β receptor type II (TβR-II), and a TGF-β receptor type I (TβR-I). Signal transduction from the receptor to the nucleus is mediated via SMADs. TGF-β expression is found in cartilage, bone, teeth, muscle, heart, blood vessels, hematopoietic cells, lung, kidney, gut, liver, eye, ear, skin, and the nervous system.

Transforming growth factor beta-2 (TGF-β2) is a secreted protein which belongs to the TGF-beta family. It is known as a cytokine that performs many cellular functions and has a vital role during embryonic development. The precursor is cleaved into mature TGF-beta-2 and LAP, which remains non-covalently linked to mature TGF-beta-2 rendering it inactive. It is an extracellular glycosylated protein. It is known to suppress the effects of interleukin dependent T-cell tumors. Defects in TGFB2 may be a cause of non-syndromic aortic disease (NSAD).

Transforming growth factor beta 2 (TGF-β2) is a member of TGF-beta superfamily that shares a characteristic cysteine knot structure. Mice with TGF-β2 gene deletion show defects in development of cardiac, lung, craniofacial, limb, spinal column, eye, inner ear and urogenital systems. All TGF-β isoforms signal via the same heteromeric receptor complex, consisting of a ligand binding TGF-β receptor type II (TβR-II), and a TGF-β receptor type I (TβR-I). Signal transduction from the receptor to the nucleus is mediated via SMADs. TGF-β expression is found in cartilage, bone, teeth, muscle, heart, blood vessels, hematopoietic cells, lung, kidney, gut, liver, eye, ear, skin, and the nervous system.

Transforming growth factor beta 3(TGFB3) is a member of a TGF -β superfamily which is defined by their structural and functional similarities. TGFB3 is secreted as a complex with LAP. This latent form of TGFB3 becomes active upon cleavage by plasmin, matrix metalloproteases, thrombospondin -1, and a subset of integrins. It binds with high affinity to TGF- β RII, a type II serine/threonine kinase receptor. TGFB3 is involved in cell differentiation, embryogenesis and development. It is believed to regulate molecules involved in cellular adhesion and extracellular matrix (ECM) formation during the process of palate development. Without TGF-β3, mammals develop a deformity known as a cleft palate.

TGF-β1 (transforming growth factor beta 1) is one of three closely related mammalian members of the large TGF-β1 superfamily that share a characteristic cystine knot structure. TGF-β1, -2 and -3 are highly pleiotropic cytokines that act as cellular switches to regulate processes such as immune function, proliferation and epithelial-mesenchymal transition. Each TGF-β isoform has some non-redundant function; for TGF-β1, mice with targeted deletion show defects in hematopoiesis and endothelial differentiation and died of overwhelming inflammation. TGF-β1 signaling begins with high-affinity binding to a type II ser/thr kinase receptor termed TGF-β RII. This receptor then phosphorylates and activates a second ser/thr kinase receptor, TGF-β RI (also called activin receptor‑like kinase (ALK)-5), or alternatively, ALK-1. This complex phosphorylates and activates Smad proteins that regulate transcription.

TGF-β1 (transforming growth factor beta 1) is one of three closely related mammalian members of the large TGF-β1 superfamily that share a characteristic cystine knot structure. TGF-β1, -2 and -3 are highly pleiotropic cytokines that act as cellular switches to regulate processes such as immune function, proliferation and epithelial-mesenchymal transition. Each TGF-β isoform has some non-redundant function; for TGF-β1, mice with targeted deletion show defects in hematopoiesis and endothelial differentiation and died of overwhelming inflammation. TGF-β1 signaling begins with high-affinity binding to a type II ser/thr kinase receptor termed TGF-β RII. This receptor then phosphorylates and activates a second ser/thr kinase receptor, TGF-β RI (also called activin receptor‑like kinase (ALK)-5), or alternatively, ALK-1. This complex phosphorylates and activates Smad proteins that regulate transcription.