1mg

Molecular Formula : C26 H35 F O7

Molecular Formula : C21H15D10Cl3FN3O

Molecular Formula : C21 H21 F O8

Molecular Formula : C21 D3 H18 F O8

Molecular Formula : C15 D5 H8 F O2

Molecular Formula : C7 D4 H5 F N3 O2 P

Molecular Formula : 13C2 C5 D2 H3 Cl2 F N2 O3

Molecular Formula : C11 D7 H4 F3 N2 O3

Molecular Formula : C43 H51 F5 O8 S

Molecular Formula : C25H28D3F3O5S

Molecular Formula : C25 H26 D5 F3 O5 S

Molecular Formula : C23H23FNNaO4

Molecular Formula : C24H19D6FNNaO4

Molecular Formula : C24H18D7FNNaO4

Molecular Formula : C14 H17 F3 N2 O3

Molecular Formula : C19H23F3N2O5

Molecular Formula : C11H14N4O4 . HCl

Molecular Formula : C1413C5H19N615NO6

Molecular Formula : C20H23N7O7

Molecular Formula : C17 D6 H14 N6 O7 S

Molecular Formula : C23 H28 N8

Molecular Formula : C613CH6N4O4

Molecular Formula : C21H28O4

Molecular Formula : C11 2H6 H9 N3 O2 . Cl H

Molecular Formula : C18 H22 N2 O4

Molecular Formula : C25 H32 N2 O10

Molecular Formula : C19H18D6N2O4

Molecular Formula : C25 H34 N3 O9 P S . Ca

Molecular Formula : C25H30D4CaN3O9PS

Molecular Formula : C37H52D4F7N6O16P

Molecular Formula : C36H54NO13P

Molecular Formula : C16 H15 N3 O4 . C H4 O3 S

Molecular Formula : C17H15D4N3O7S

Molecular Formula : C27H50FN4O5PS

Molecular Formula : C11 H16 F N3 S2

Fractalkine, also named neurotactin, is a novel chemokine recently identified through bioinformatics. Fractalkine has a unique C-X3-C cysteine motif near the amino-terminus and is the first member of a fourth branch of the chemokine superfamily. Unlike other known chemokines, fractalkine is a type 1 membrane protein containing a chemokine domain tethered on a long mucin-like stalk. Human fractalkine cDNA encodes a 397 amino acid (aa) residue membrane protein with a 24 aa residue predicted signal peptide, a 76 aa residue chemokine domain, a 241 aa residue stalk region containing 17 degenerate mucin-like repeats, a 19 aa residue transmembrane segment and a 37 aa residue cytoplasmic domain. The extracellular domain of human fractalkine can be released, possibly by proteolysis at the dibasic cleavage site proximal to the membrane, to generate soluble fractalkine. The soluble chemokine domain of human fractalkine was reported to be chemotactic for T cells and monocytes while the soluble chemokine domain of mouse fractalkine was reported to chemoattract neutrophils and T-lymphocytes but not monocytes.

Chemokine (C-X3-C motif) ligand 1 (CX3CL1) is a known member of the CX3C chemokine family. It is also commonly known under the names fractalkine (in humans) and neurotactin (in mice). The polypeptide structure of CXC3L1 differs from the typical structure of other chemokines. For example, the spacing of the characteristic N-terminal cysteines is different; there are three amino acids separating the initial pair of cysteines in CX3CL1, while there are none in CC chemokines and only one in CXC chemokines. CX3CL1 is produced as a long protein (with 373-amino acid in humans) with an extended mucin-like stalk and a chemokine domain on top. The mucin-like stalk allows it to bind to the surface of certain cells. Soluble CX3CL1 potently chemoattracts T cells and monocytes, while the cell-bound chemokine promotes strong adhesion of leukocytes to activated endothelial cells, where it is primarily expressed. CX3CL1 can signal through the chemokine receptor CX3CR1.

Molecular Formula : 4 C6 H7 K5 O21 S5

Molecular Formula : C11 H17 N O9 . 2Na

Molecular Formula : C21 H22 F N3 O3

Molecular Formula : C38H55F5O9S

Molecular Formula : C32H46F5NaO6S2

Molecular Formula : C26 H34 O7

Molecular Formula : C16 H26 O4

Molecular Formula : 13C4H4O4

Molecular Formula : C22 H25 N3 O3

Molecular Formula : C34 H59 N O15

Molecular Formula : C34 H59 N O14

Molecular Formula : C34 H59 N O14

Molecular Formula : C34 H59 N O14