Ambient

Laemmli SDS-Sample Buffer 6X, Non-Reducing

Laemmli SDS-Sample Buffer 6X, Non-Reducing

Molecular Formula : C15H12F3N2NaO2

Molecular Formula : C15H12F3N2NaO2

Molecular Formula : C22H29N3O5S

Molecular Formula : C22H29N3O5S

Lymphocyte activation gene-3 (LAG-3), also known as CD223, is a cell-surface 70kDa molecule belong to Ig superfamily with diverse biologic effects on T cell function. LAG-3 is a CD4 homolog originally cloned in 1990. The gene for LAG-3 lies adjacent to the gene for CD4 on human chromosome 12 (12p13) and is approximately 20% identical to the CD4 gene. human LAG-3 shares 70%, 67%, 76%, and 73% aa sequence identity with mouse, rat, porcine, and bovine LAG-3, respectively. LAG-3 is expressed on B cells, NK cells, tumor-infiltrating lymphocytes, and a subset of T cells. LAG-3 was relatively overexpressed on transgenic T cells rendered anergic in vivo by encounter with cognate self-antigen. LAG-3 negatively regulates murine T cell activation and homeostasis. LAG-3 activates antigen-presenting cells through MHC class II signaling, leading to increased antigen-specific T-cell responses in vivo. Blocking or knocking out LAG-3 in neuronal cultures or in animals mitigated the transmission of α-synuclein between neurons, and dampened accumulation as well as toxic effects of the fibrils on motor function. Anti-LAG3 antibodies are already being tested as cancer treatments, it could also make a useful therapeutic target to treat Parkinson’s and other synucleinopathies.

Lymphocyte activation gene-3 (LAG-3), also known as CD223, is a cell-surface 70kDa molecule belong to Ig superfamily with diverse biologic effects on T cell function. LAG-3 is a CD4 homolog originally cloned in 1990. The gene for LAG-3 lies adjacent to the gene for CD4 on human chromosome 12 (12p13) and is approximately 20% identical to the CD4 gene. human LAG-3 shares 70%, 67%, 76%, and 73% aa sequence identity with mouse, rat, porcine, and bovine LAG-3, respectively. LAG-3 is expressed on B cells, NK cells, tumor-infiltrating lymphocytes, and a subset of T cells. LAG-3 was relatively overexpressed on transgenic T cells rendered anergic in vivo by encounter with cognate self-antigen. LAG-3 negatively regulates murine T cell activation and homeostasis. LAG-3 activates antigen-presenting cells through MHC class II signaling, leading to increased antigen-specific T-cell responses in vivo. Blocking or knocking out LAG-3 in neuronal cultures or in animals mitigated the transmission of α-synuclein between neurons, and dampened accumulation as well as toxic effects of the fibrils on motor function. Anti-LAG3 antibodies are already being tested as cancer treatments, it could also make a useful therapeutic target to treat Parkinson’s and other synucleinopathies.

Molecular Formula : 2[C17 H12 Cl N2 O4 S] . Ba

Molecular Formula : 2[C17 H12 Cl N2 O4 S] . Ba

Molecular Formula : 2[C17 H12 Cl N2 O4 S] . Ba

lambda-Carrageenan

Laminaran, from Eisenia Bicyclis

Laminaran, from Eisenia Bicyclis

Laminarin

Laminarin

Molecular Formula : C18 H30 O14 X2

Molecular Formula : C18 H30 O14 X2

Molecular Formula : C18 H30 O14 X2

Molecular Formula : C8 H11 N3 O3 S

Molecular Formula : C8 H11 N3 O3 S

Molecular Formula : C8 H11 N3 O3 S

Molecular Formula : C8 H11 N3 O4 S

Molecular Formula : C8 H11 N3 O4 S

Molecular Formula : C8 H11 N3 O4 S

Molecular Formula : C8H9N3O4S

Molecular Formula : C8 H9 N3 O4 S

Molecular Formula : C8H9N3O4S

Molecular Formula : C8H12N3O6PS:[C6H15N]ₓ

Molecular Formula : C8H12N3O6PS:[C6H15N]ₓ

Molecular Formula : C8 H11 N3 O5 S

Molecular Formula : C8 H11 N3 O5 S

Molecular Formula : C8 H11 N3 O5 S

Molecular Formula : C713CH9D2N3O3S

Molecular Formula : C713CH9D2N3O3S

Molecular Formula : 13C C7 H11 15N2 N O3 S

Molecular Formula : 13C C7 H11 15N2 N O3 S

Lamotrigine

Lamotrigine

Molecular Formula : C19 H14 Cl4 N10

Molecular Formula : C19 H14 Cl4 N10

Molecular Formula : C19 H14 Cl4 N10

Molecular Formula : C19 H14 Cl4 N10

Molecular Formula : C19H14Cl4N10

Molecular Formula : C9 H7 Cl2 N5 . C2 H6 O4 S

Molecular Formula : C9 H7 Cl2 N5 . C2 H6 O4 S

Molecular Formula : C9 H7 Cl2 N5 . C2 H6 O4 S