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Freund’s Complete Adjuvant, Mycobacterium butyricum, consists of heat-killed Mycobacterium butyricum in non-metabolizable oils (paraffin oil) and surfactant (Arlacel A). Components are thoroughly mixed in controlled proportions and autoclaved prior to being vialed.

Features of Freund’s Complete Adjuvant (FCA):

• Also called Complete Freund’s Adjuvant (CFA).
• FCA can be utilized to produce water-in-oil emulsions of antigens.
• FCA can significantly enhance the immune response to immunogens by inducing a potent and long-lasting immune response.
• FCA contains heat-killed Mycobacterium butyricum, which help to stimulate the immune system.
• FCA is often used for initial immunization.

This product is made by a modification of Freund’s technique, in which 25 mg of Mycobacterium is suspended in a mixture of 7.5 mL Arlacel A and 42.5 mL paraffin oil. An adjuvant is a material that when administered enhances the antibody response of animals injected with antigen.

This product is made by a modification of Freund’s technique, in which 25 mg of Mycobacterium is suspended in a mixture of 7.5 mL Arlacel A and 42.5 mL paraffin oil. An adjuvant is a material that when administered enhances the antibody response of animals injected with antigen.

This product is made by a modification of Freund’s technique, in which 25 mg of Mycobacterium is suspended in a mixture of 7.5 mL Arlacel A and 42.5 mL paraffin oil. An adjuvant is a material that when administered enhances the antibody response of animals injected with antigen.

Freund’s incomplete adjuvant is used for the boosts. Prepared from non-metabolizable oils (paraffin oil and mannide monooleate)

Freund’s incomplete adjuvant is used for the boosts. Prepared from non-metabolizable oils (paraffin oil and mannide monooleate)

Freund’s Incomplete Adjuvant is a commonly used immunological adjuvant that contains non-metabolizable oils (paraffin oil) and surfactant (Arlacel A). Components are thoroughly mixed in controlled proportions and autoclaved prior to being vialed.

Features of Freund’s Incomplete Adjuvant (FIA):

• Also called Incomplete Freund’s Adjuvant (IFA).
• FIA can be utilized to produce water-in-oil emulsions of antigens.
• By forming a depot at the injection site and stimulating the production of antibody-producing plasma cells, FIA predominantly induces a Th2-biased response.
• FIA is typically used for subsequent boost immunizations.

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