Shop

Polyclonal Antibodies

Polyclonal Antibodies

Polyclonal Antibodies

Polyclonal Antibodies

Polyclonal Antibodies

Polyclonal Antibodies

Polyclonal Antibodies

Monoclonal Antibodies

Monoclonal Antibodies

Polyclonal Antibodies

Polyclonal Antibodies

Span 40, (=Sorbitan Monopalmitate)

Span 40, (=Sorbitan Monopalmitate)

Span 60, (=Sorbitan Monostearate)

Span 60, (=Sorbitan Monostearate)

Span 80, (=Sorbitan Monooleate)

Span 80, (=Sorbitan Monooleate)

Span 83, (=Sorbitan Sesquioleate)

Span 83, (=Sorbitan Sesquioleate)

Span 85, (=Sorbitan Trioleate)

Span 85, (=Sorbitan Trioleate)

Polyclonal Antibodies

Polyclonal Antibodies

SPARC, an acronym for ’secreted protein, acidic and rich in cysteine’, is also known as osteonectin or BM-40. It is the founding member of a family of secreted matricellular proteins with similar domain structure. The 303 amino acid , 43 kDa protein contains a 17 aa signal sequence, an N-terminal acidic region that binds calcium, a follistatin domain containing Kazal-like sequences, and a C-terminal extracellular calcium (EC) binding domain with two EF-hand motifs. SPARC is produced by fibroblasts, capillary endothelial cells, platelets and macrophages, especially in areas of tissue morphogenesis and remodeling. SPARC shows context-specific effects, but generally inhibits adhesion, spreading and proliferation, and promotes collagen matrix formation. For endothelial cells, SPARC disrupts focal adhesions and binds and sequesters PDGF and VEGF. SPARC is abundantly expressed in bone, where it promotes osteoblast differentiation and inhibits adipogenesis.

SPARC, an acronym for ’secreted protein, acidic and rich in cysteine’, is also known as osteonectin or BM-40. It is the founding member of a family of secreted matricellular proteins with similar domain structure. The 303 amino acid , 43 kDa protein contains a 17 aa signal sequence, an N-terminal acidic region that binds calcium, a follistatin domain containing Kazal-like sequences, and a C-terminal extracellular calcium (EC) binding domain with two EF-hand motifs. SPARC is produced by fibroblasts, capillary endothelial cells, platelets and macrophages, especially in areas of tissue morphogenesis and remodeling. SPARC shows context-specific effects, but generally inhibits adhesion, spreading and proliferation, and promotes collagen matrix formation. For endothelial cells, SPARC disrupts focal adhesions and binds and sequesters PDGF and VEGF. SPARC is abundantly expressed in bone, where it promotes osteoblast differentiation and inhibits adipogenesis.

Polyclonal Antibodies

Polyclonal Antibodies

Spare 10 mL Holders for Z287-0810H Rotor, 2/pk

Spare Parts and Accessories for 142 and 293mm Disc Filter Holder – Hose assembly kit includes clamp and PTFE gasket, type 316 stainless steel inlet/outlet adapter, 3.8 cm (1.5 in.) sanitary to 9.5mm (3/8 in.) hose barb

Spare Parts and Accessories, 25 mm In-Line Filter Holder – Underdrain disc, Type 316 stainless steel

Spare Parts and Accessories, 25mm In-Line Filter Holder – Support screen, Type 316 stainless steel

SPARE PARTS KIT K840-0XTK

Spare reservoir bottle, 2000mL, amber, Boro 3.3, NS 29/32

Spare reservoir bottle, 2000mL, clear, Boro 3.3, NS 29/32

Spare seal kit contains 5 PTFE gaskets, 10 Viton O-rings and 1 stainless steel hose barb adapter to 6.4mm (1/4 in.) ID tubing

Polyclonal Antibodies

Polyclonal Antibodies

Polyclonal Antibodies

Polyclonal Antibodies

Polyclonal Antibodies

Polyclonal Antibodies