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Lysine Iron Agar, 5 kg

Lysozyme, Egg White, Crystalline Powder

m FC Agar, 5 kg

m-Aminophenol

m-Cresol Purple

Macrophage-Colony Stimulating Factor (M-CSF), also known as Colony Stimulating Factor-1 (CSF-1), is a hematopoietic growth factor. It can stimulate the survival, proliferation and differentiation of mononuclear phagocytes, in addition to the spreading and motility of macrophages. In mammals, it exits three isoforms, which invariably share an N-terminal 32-aa signal peptide, a 149-residue growth factor domain, a 21-residue transmembrane region and a 37-aa cytoplasmictail. M-CSF is mainly produced by monocytes, macrophages, fibroblasts, and endothelial cells. M-CSF interaction with its receptor, c-fms, has been implicated in the growth, invasion, and metastasis of of several diseases, including breast and endometrial cancers. The biological activity of human M-CSF is maintained within the 149-aa growth factor domain, and it is only active in the disulfide-linked dimeric form, which is bonded at Cys63.

m-HPC Agar, 5 kg

MacConkey Agar, 5 kg

MacConkey Broth, 5 kg

MAGNA Nylon Membrane, Loose pore size, (W x L): 22 x 22 cm.

MAGNA Nylon Membranes, Sheets, 0.22 um, 20 x 20 cm

MagnaProbe Nylon Transfer Membrane

MagnaProbe Nylon Transfer Membrane, Dimensions: 20 x 20 cm

MagnaProbe Nylon Transfer Membrane, Dimensions: 30 x 30 cm

Magnesium Ascorbyl Phosphate

Magnesium Chloride, Anhydrous

Magnesium Chloride, Anhydrous

Magnesium Oxide, Powder, Reagent, ACS

Magnesium Sulfate, Anhydrous, USP

Magnesium Sulfate, Anhydrous, USP

Maleic Acid

Maleic Acid Disodium Salt, Anhydrous

Maleimide

Malt Extract Agar, 5 kg

Maltotriose

Mannan

Mannitol Salt Agar, 5 kg

CCL2, also known as monocyte chemotactic and activating factor (MCAF), was initially purified independently by two groups based on its ability to chemoattract monocytes. Subsequent to its cloning and sequencing, it became evident that this protein is also identical to the product of the human JE gene. The JE gene, originally identified in mouse fibroblasts, is a plateletderived growth factor (PDGF)inducible gene. The human CCL2 cDNA encodes a 99 amino acid residue precursor protein with a 23 residue hydrophobic signal peptide that is cleaved to generate the 76 residue mature protein. Natural CCL2 is heterogeneous in size due to the addition of Olinked carbohydrates and sialic acid residues. In addition to fibroblasts; tumor cells, smooth muscle cells, endothelial cells, and mononuclear phagocytes can also produce CCL2 either constitutively or upon stimulation by various stimuli. CCL2 is a member of the β (CC) subfamily of chemokines. Recently, the existence of MCP2 and MCP3 with 62% and 73% amino acid identity respectively, to CCL2 have been reported.

Chemokine (C-C motif) ligand 2 (CCL2) is also referred to as monocyte chemotactic protein 1 (MCP1) and small inducible cytokine A2. CCL2 is a small cytokine that belongs to the CC chemokine family. CCL2 recruits monocytes, memory T cells, and dendritic cells to the sites of inflammation produced by either tissue injury or infection. CCL2 is implicated in the pathogeneses of several types of disease characterized by monocytic infiltrates, such as psoriasis, rheumatoid arthritis and atherosclerosis. CCL2 is anchored in the plasma membrane of endothelial cells by glycosaminoglycan side chains of proteoglycans. CCL2 is primarily secreted by monocytes, macrophages and dendritic cells. CCL2 can signal through the CCR2 receptor.

Mebendazole

Meclofenamate Sodium, USP

Mecobalamin, JP